Tumor de Klatskin: diagnóstico, evaluación preoperatoria y consideraciones Es un tumor agresivo con una resecabilidad al diagnóstico del 47% y una. Cholangiocarcinomas (CCCs) are malignancies of the biliary duct system Perihilar tumors, also called Klatskin tumors (after Klatskin’s description of them in The etiology of most bile duct cancers remains undetermined. Klatskin tumor is an extra-hepatic cholangiocarcinoma (CCA, see this term) arising in the junction of the main right or left hepatic ducts to form the common.

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HPB Oxford15pp. Cir Esp, 86canced. Arch Surg ; To summarise, the majority of PHC is adenocarcinomas with a periductal growth pattern that gives them a poorer prognosis, while the variant with intraductal growth is klahskin least frequent, although it has a better prognosis. The basic differences are shown in Table 1and they chiefly consist of From Wikipedia, the free encyclopedia.

AJCC 7th edition of TNM staging accurately discriminates outcomes of patients with resectable intrahepatic cholangiocarcinoma: Preoperative biliary drainage before resection for cholangiocarcinoma Pro. Local involvement should now not be a criterion for non-resectability, klarskin condition that we are able to achieve an R0 with surgical resection.

Findings on either study suggestive of Klatskin tumor include a dilated intrahepatic biliary tree, a normal or collapsed gallbladder and extrahepatic biliary tree, and a normal pancreas.

Klatskin tumor – Wikipedia

MR or computerised tomography may be used for volumetric testing, depending on the type of apparatus or computer programmes available in each hospital. Segmental liver resection for hilar cholangiocarcinoma. World Journal of Gastroenterology.


Major liver resection for carcinoma in jaundiced patients without preoperative klatsin drainage. Yale Journal of Biology and Medicine. Se continuar a navegar, consideramos que aceita o seu uso.

Scand J Surg ; The concept of perihilar cholangiocarcinoma is valid. Is it Still Worthwhile? Cholangiography should define not only the location, but also visualize the uppermost extent of the tumor to determine the limits of resectability. Abdominal computerised axial tomography: Klatskin tumors Keith D LillemoeM. Subsequently, a series of 13 patients with this diagnosis was reported by Klatskin ve Serous microcystic adenoma Intraductal papillary mucinous neoplasm Mucinous cystic neoplasm Solid pseudopapillary neoplasm Pancreatoblastoma.

Metastasis to regional lymph nodes is frequent. The importance of this differentiation lies in the variations in survival depending on the subtype in question. Therefore, percutaneous transhepatic catheters provide the best access for palliation of inoperable hilar cholangiocarcinoma. Only comments written in English can be processed.

As resectability differs from group to group, while the tendency is towards increasingly aggressive treatments, its value will depend on the criteria for non-resectability klatsin each centre. Digestive system neoplasia Hepatology. Rev Col Gastroenterol klatski en prensa. Specific antibiotic prophylaxis based on bile cultures is required to prevent postoperative infectious complications in pancreatoduodenectomy patients who have undergone preoperative biliary drainage.

From randomized studies to real medical practice. Surgical treatment in proximal bile duct cancer.

Klatskin tumor

Am J Gastroenterol ; Prognostic significance of lymph node ratio after resection of peri-hilar cholangiocarcinoma. The levels in serum of these markers are strongly influenced by xancer obstruction and jaundice due to their biliary elimination. Subscribe to our Newsletter.


Continuing navigation will be considered as acceptance of this use. If there cahcer doubt about spread into the lymph nodes which may contraindicate surgery positron emission tomography or fine needle aspiration endoscopy is recommended.

Klatskin tumors – Surgical Treatment – NCBI Bookshelf

J Comput Assist Tomogr ; Diagnosis of klatekin venous invasion by pancreatobiliary carcinoma: Relief of biliary blockage and resection of disease are the main goals of treatment.

Please review our privacy policy. Major hepatectomies are safe in patients with cholangiocarcinoma and jaundice.

These catheters, however, may be associated with direct complications such as bleeding and infection. Only 2 years follow-up. Br J Surg, 96pp.

Autoimmune cholangitis and primary biliary non-Hodgkin’s lymphoma are differential diagnoses of Klatskin tumors. Scandinavian Journal of Gastroenterology. This fall is chiefly due dw improvement in non-invasive tests such as MR-cholangiography. Palliative treatment involves the placement of plastic or metallic biliary stents. Tumor debajo la confluencia. A systematic review and meta-analysis. This technique demonstrates hepatic parenchyma and it’s accurate for detecting nodular carcinomas and infiltrating lesions.

Some authors recommend that drained patients receive prophylactic antibiotics suitable for klatwkin biliary cultures.