Eccrine hidradenoma is a rare benign cutaneous neoplasm, believed to arise from the distal excretory duct of the eccrine sweat glands [1]. Because a. Hidradenoma refers to a benign adnexal tumor of the apical sweat gland. Another name for tumors that were previously believed to strictly derive from specific sweat gland types may, in fact, derive from both eccrine or apocrine glands. Hidradenoma is a cutaneous, often benign tumour of the sweat glands. Also known by various other names such as nodular hidradenoma, eccrine acrospiroma.

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It usually presents as a superficial dermal lesion and hence it is diagnosed early and hidradeboma excised without much investigation. Atypical and malignant hidradenomas: Middle East Afr J Ophthalmol ; Sweat gland lesions originate from sweat gland or sweat duct cell lines. It is commonly seen in adults. Computed tomography showed a large mass occupying the parotid space, the masticatory space, and the temporal region, with infiltrations into the temporalis muscle and pterygoid muscles.

The tumor mass extended to the cranial base around the right foramen ovale without any intracranial extension black arrow. Footnotes No potential conflict of interest relevant to this article was reported.

They are most commonly found around the eyes and on the eyelidsbut they can occur on other sites. A giant benign clear cell hidradenoma on the anterior trunk. Winkelmann RK, Wolff K. However, a case of a benign giant eccrine hidradenoma infiltrating the deeper hidradenlma beyond the muscle layer to the cranial base has not been reported thus far.

Aniruddha Tekkatte Jagannatha,Mansoor A. Solid-cystic hidradenoma of the skin: This cell mass showed two distinct cell populations.

Giant Eccrine Hidradenoma Mimicking a Malignant Tumor of the Salivary Gland

Apocrine adenocarcinoma hidtadenoma develop within recognisable benign tumours allowing classification as follows. A differential diagnosis of soft tissue sarcoma like dermatofibrosarcoma protuberans was considered so was hidradenoma.

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When multiple, they are sometimes described as poromatosis. During which it had gradually progressed in size over sccrine years but showed rapid progression in size in the past hidradennoma months.

On Histopathological examination both solid and cystic components are present with characteristic clear cells, which contain a large amount of glycogen and thus appear clear under light microscopy. Integumentary neoplasia Epidermal nevi, neoplasms, cysts Oncology stubs Epidermal nevi, neoplasm, cyst stubs.

Neoplasms of the nailbed. Cylindroma Dermal cylindroma Syringocystadenoma papilliferum Papillary hidradenoma Hidrocystoma Apocrine gland carcinoma Apocrine nevus. Laboratory findings including all hematologic and biochemical examinations showed no abnormalities.

Although it was difficult to secure clear resection hidfadenoma the cranial base because of the poor accessibility and technical difficulty, surgery was planned to preserve the function of major neurovascular structures involved with the tumor. Histochemistry shows positive carcinoembryonic antigen CEA immunostaining. National Center for Biotechnology InformationU.

Irwin M et al.

Agri and Aquaculture Journals Dr. In contrast, pleomorphic adenoma is highly variable in appearance, even within individual tumors. He had difficulty opening his mouth and hidradenomq his right eyelid.

The tumor is usually confined to the dermis or subcutaneous layer without involving the deep structures. Rook’s Textbook of Dermatology 8th ed. It occurs commonly in middle-aged and older adults, and can be found anywhere on the body without predilection for a particular site [ 2 ].

However if it is not possible due to any reason, one must err on the side of safety and perform a wide local excision with appropriate margins.

Eccrine glands play an important role in the regulation of body temperature. Skin biopsy of poroma shows a growth of terminal duct cells. J Neurosci Rural Pract ;5: Sweat gland lesions generally have variable apocrine or eccrine differentiation.

Hidradenoma: A Skin Adnexal Tumour, Case Report and Literature Review | OMICS International

In contrast, apocrine glands produce an oily fluid rich in triglycerides and fatty acids — subsequent colonisation by anaerobic bacteria results in body odour. Histopathology of the wide local excision of the tumour revealed benign nodular hidradenoma. The tumor mass compressed the internal jugular vein, displaced the external carotid artery inferiorly, and extended to the cranial base around the right foramen ovale without intracranial extension Fig.


True cut biopsy was attempted and was also inconclusive. When tumors show malignant characteristics, they are known as hidradenocarcinoma. The narrow ducts are often lined by a row of cuboidal cells.

Giant Eccrine Hidradenoma Mimicking a Malignant Tumor of the Salivary Gland

Hidradenoma may be solid or produce a watery discharge. Nodular hidradenocarcinoma on the scalp of a young woman: No evidence of atypical mitosis or necrosis seen.

Eccrine hidradenoma is typically characterized by two types of cells: They present as a slowly growing, solitary nodule and can measure up to several centimetres in size. Traditionally these lesions have been categorized under either the apocrine or eccrine groups, but significant overlaps do exist.

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Syringomas are more commonly found in the Asian population, and there is an association with Down syndrome. At postoperative 3 weeks, we performed a static sling procedure with a prolene suture 2 and Endotine Ribbon Coapt Systems Inc.

Poroid hidradenoma refers to a hybrid lesion with features of hidradenoma and poroma. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, hidradenoms the original author and source are credited. These findings were consistent with a malignant tumor of the salivary gland.